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13:00 - 14:00 17 September 2015

External Seminar: Multimodal inputs alter neural circuitry in a hidden hearing loss model of tinnitus

Location

The Lecture Theatre | UCL Ear Institute (link Map)
332 Grays Inn Road | London | WC1X 8EE | United Kingdom

Open to: Academic | Student

Speaker information

Prof Susan Shore, Kresge Hearing Research Institute, University of Michigan

Over the past decade, my lab has been studying the contributions of multisensory systems to auditory processing. In particular, we discovered that ‘touch-sensitive’ neurons in the brain, that receive input from the face and head, send neural projections to the auditory system. These projections terminate in the first brain station of auditory system, the cochlear nucleus, which receives input directly from the cochlea. Our work has shown that neurons from somatosensory systems can alter the cochlear nucleus firing patterns. Most remarkably, after deafness, there is a strong enhancement in somatosensory influences on the cochlear nucleus, which reflect homeostatic plasticity. Our recent work demonstrates that in animals with behaviorally-confirmed tinnitus, a major change observed in the principal output neurons of the cochlear nucleus was a long-term increase excitation from the somatosensory system, which was stimulus-timing-dependent. (Abbreviated abstract)


Contact

Kate Faxen
Please email | kate.faxen@ucl.ac.uk


Links

Press release
Press release


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