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18:00 - 19:00 8 April 2014

Molecules of sickness and death: Understanding the structural basis of foot-and-mouth disease


Haldane Room | Wilkins Building (link Map)
Gower St | London | WC1E 6BT | United Kingdom

Open to: Academic | Alumni | Public | Student
Ticketing: Pre-booking essential

Speaker information

Stephen Curry, Professor Structural Biology, Imperial College

Foot-and-mouth disease virus, the pathogen that causes worldwide devastation of animal livestock, has a beguiling simplicity in its construction: it contains just a single gene. However, even with that limited resource the virus can infect and take over animal cells in a matter of hours, turning them into virus factories. Our research aims to understand the molecular and structural basis of virus replication with a view to stopping the virus in its tracks. Although there are effective vaccines for FMD, technical and political considerations complicate their use and there is still a need to develop antiviral drugs.

Stephen Curry will discuss the broader issues of FMD control and report on our ongoing efforts to understand the structure and druggability of a key viral enzyme: the 3C protease.


Mark Huckvale
+44 (0)20 7679 4087 | m.huckvale@ucl.ac.uk


Book attendance