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16:00 - 17:00 4 September 2017

The Sainsbury Wellcome Centre Seminar: “Episodic memory encoding by a place cell sub-population”

Location

Ground floor Lecture Theatre, Sainsbury Wellcome Centre (link Map)
25 Howland Street | London | W1T 4JG | United Kingdom

Open to: Academic | Student

Abstract: Study of the hippocampal place cell system has greatly enhanced our understanding of memory encoding for distinct places, but it is not clear how episodic memories for distinct experiences occurring within familiar environments are encoded. We found that as rats learned about the locations of aversive stimuli in a spatial decision making task, a subset of the CA1 place cell population shifted its coordination by the ongoing theta rhythm, remapped, and became integrated into Hebbian cell assemblies dominated by non-remapping cells. During consolidation of learning, remapping cells participated more in awake replay events relative to non-remapping cells, and with additional training, developed more correlated firing patterns in aversive regions of the environment.

Speaker: Dr Jake Ormond, Lab for Neural Circuitry of Memory, RIKEN Brain Science Institute

Host: John O'Keefe


Contact

Karen Fergus
+44 (0)20 3108 8004 | Karen.Fergus@ucl.ac.uk


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