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12:30 - 13:30 10 January 2018

Network Motif Families for Lung Cancer Diagnostics: A World Community Grid Approach


Room G01,The Farr Institute (link Map)
222 Euston RoadKings Cross | London | NW1 2DA | United Kingdom

Open to: Academic | Student

Despite smoking cessation, and advances in detection and treatment, lung cancer remains the primary cause of cancer-related death 2014; Siegel, 2015, and non-small cell lung cancer (NSCLC) accounts for about 80-85% of all cases. The overall survival rate for lung cancer has marginally improved in the past decades, from 13% to 16%. The asymptomatic nature of this disease does not result in diagnosis until advanced stages of the disease. Over recent decades, numerous studies have analysed NSCLC using diverse ``omic'' platforms to identify a large pool of signatures for detection and prognosis. However, translating these into clinical practice remains challenging; signatures often do not validate in other cohorts or by different biological assays, and there are thousands of possible combinations to consider.....


UCL Institute of Digital Health
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