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13:00 - 14:00 16 October 2014

Queen Square MS Centre seminar: In vivo, postmortem and histological investigations into thalamic grey matter pathology in multiple sclerosis


Gilliatt Lecture Theatre | UCL Institute of Neurology (link Map)
Queen Square | London | United Kingdom

Open to: Academic | Student

Speaker information: Steven HP van de Pavert. Abstract: The extent and clinical relevance of GM pathology in MS are increasingly recognised. To understand GM pathology, three independent studies are done to answer the following questions. 1) Do GM lesions and GM atrophy co-localise, and what is their independent contribution to clinical disability in vivo? 2) Can thalamic GM pathology, as detected by in vivo MRI, be explained by prior damage to connecting WM fibres or connecting cortical areas? 3) What are the underlying histopathological substrates of MR abnormalities of GM pathology? Combined, this work is aimed to gain a greater insight in the pathophysiology of GM injury in MS.


Tina Holmes